Abstract
Gold(I) complexes containing monodentate PIII ligands built upon methylated α-cyclodextrins have been synthesized and assessed in the cycloisomerization of 1,6-enynes, two of the reactions studied involving prochiral substrates. Their performance was compared with that of previously reported mononuclear and dinuclear α- and β‐cyclodextrin-based AuI complexes. Enantiodiscrimination was found to be strongly dependent on the ability of the ligand to position metal-coordinated substrates inside the cyclodextrin core.
Reference
Zeyneb Kaya, Lucile Andna, Dominique Matt, Embarek Bentouhami, Jean‐Pierre Djukic, Dominique Armspach
A Comparative Study of Confining Ligands Derived from Methylated Cyclodextrins in Gold-Catalyzed Cycloisomerization of 1,6-Enynes
EurJOC - DOI: 10.1002/ejoc.201900631
Contact chercheur
Dominique Armspach, équipe ECMC, Institut de Chimie (UMR 7177).
![[Translate to English:]](/websites/_processed_/0/4/csm_signature-unistra_16a9ad672e.png)
![[Translate to English:]](/websites/_processed_/0/e/csm_logo-cnrs_c35686510a.png){kind=logo}
![[Translate to English:]](/websites/_processed_/9/4/csm_logo-fondation-lehn_e04fdb6c72.png){kind=logo}