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The Institute of Chemistry (UMR7177) is pleased to welcome Professor Marine DESAGE-EL MURR, head of the new OMECA team (Objects, MEtals and CAtalysis).
After a degree in chemical engineering (CPE Lyon and ENSCP), Marine DESAGE-EL MURR completed a doctoral thesis at CEA Saclay, under the direction of Dr. Charles MIOSKOWSKI, defended in 2003. She then joined the University of Newcastle- upon-Tyne, UK for a postdoctoral fellowship in medicinal chemistry. She was appointed “Maître de Conférences" (Associate Professor) in 2007 at University Pierre and Marie Curie (UPMC), where she initiated a new research topic in the Institute of Molecular Chemistry of Paris (IPCM) on the use of redox-active ligands in cooperative catalysis, thanks to a junior researcher ANR grant. The main scientific achievements to date concern the development and study of unconventional organometallic and / or catalytic mechanisms and in particular the influence of the ligand's oxidation state on the reactivity of the metal. The OMECA team's research aims to develop catalytic systems and complex architectures using multifunctional redox structures.
Marine DESAGE-EL MURR is also a member of the European network COST Action ECOSTBio (Explicit Control Over Spin-states in Technology and Biochemistry) and was a board member of the Ile-de-France section of the Société Française de Chimie.
Publications récentes représentatives / key publications:
Copper-catalysed aziridination with redox-active ligands: molecular spin catalysis, Ren, Y.; Cheaib, K.; Jacquet, J.; Vezin, H.; Fensterbank, L.; Orio,M.; Blanchard, S.; Desage-El Murr, M., Chem. Eur. J. 2018, doi: 10.1002/chem.201705649.
Circumventing metallic intrinsic reactivity: radical generation with redox-active ligands,Jacquet, J.; Cheaib, K.; Ren, Y.; Vezin, H.; Orio,M.; Blanchard, S.; Fensterbank, L.; Desage-El Murr, M., Chem. Eur. J.2017, 23, 15030–15034.
C–N bond formation from a masked high-valent copper complex stabilized by redox non-innocent ligands,Jacquet, J.; Chaumont, P.; Gontard, G.; Orio,M.; Vezin, H.; Blanchard, S.; Desage-El Murr, M.; Fensterbank, L., Angew. Chem. Int. Ed.2016, 55, 10712–10716.
Redox-ligand sustains controlled generation of CF3 radicals by well-defined copper complex,Jacquet, J.; Blanchard, S.; Derat, E.; Desage-El Murr, M.; Fensterbank, L., Chem. Sci.2016, 7, 2030–2036. Communiqué sur le site de l'Institut de Chimie du CNRS «En direct des laboratoires» www.cnrs.fr/inc/communication/direct_labos/desage.htm.
Iminosemiquinone radical ligands enable access to a well-defined redox-active CuII–CF3 complex,Jacquet, J.; Salanouve, E.; Orio, M.; Vezin, H.; Blanchard, S.; Derat, E.; Desage-El Murr, M.; Fensterbank, L., Chem. Commun.2014, 50, 10394–10397.
Tandem C–H activation/arylation catalyzed by low-valent iron complexes bearing bisiminopyridine ligands, Salanouve, E.; Bouzemame, G.; Blanchard, S.; Derat, E.; Desage-El Murr, M.; Fensterbank, L., Chem. Eur. J.2014, 20, 4754–4761.