Abstract: In this study, water-soluble colloidal platinum nanoparticles (Pt NPs) have been stabilized with novel thiolated cyclodextrins (CD-SH) and their catalytic performance has been investigated. We varied the size of the CD cycle (α-CD/β-CD), the degree of thiolation (one or two thiol groups per CD), and the CD/Pt molar ratio (0.5; 0.2; 0.1; 0.05) to find the best performing water-soluble,...[more]
Abstract: A Kohn–Sham (KS) density-functional energy expression is derived for any (ground or excited) state within a given many-electron ensemble along with the stationarity condition it fulfills with respect to the ensemble density, thus giving access to both physical energy levels and individual-state densities, in principle exactly. We also provide working equations for the evaluation of the...[more]
Abstract: The discovery of a stable organic radical formed under mild, clean, and efficient light-mediated conditions is reported. The structure of the stable acridinium-based radical photoproduct was unambiguously established by single-crystal X-ray diffraction, mass spectrometry, and in solution by EPR, UV/vis, and NMR spectroscopies. The photochemical mechanism of its formation has been...[more]
Abstract: In this review, the difference between π-mers (pimers) and π-dimers (pi-dimers) will be discussed. Often interchanged or confused in the literature, these two radical interactions lead to different or even opposite physico-chemical behaviors. This review aims at clarifying the terms π-mers and π-dimers and at describing their main physico-chemical properties to address their...[more]
Abstract: Imaging extracellular Cu2+ in vivo is of paramount interest due to its biological importance in both physiological and pathological states. Magnetic resonance imaging (MRI) is a powerful technique to do so. However, the development of efficient MRI contrast agents selective for Cu2+, particularly versus the more abundant Zn2+ ions, is highly challenging. We present here an innovative...[more]
L’Institut de Chimie de Strasbourg a l’honneur de vous informer que le projet «Conception d’un ligand bioinspiré à 64/67Cu pour des applications théranostiques» déposé par Laurent RAIBAUT (équipe BCB, Bométaux et Chimie Biologique) dans le cadre de l’appel à projets Emergence@CNRSChimie 2025 a été retenu pour financement. L’objectif de cet appel à projets CNRS qui est relancé pour la huitième...[more]
Abstract: The lipid cis-trans isomerase (Cti) is a periplasmic heme-c enzyme found in several bacteria including Pseudomonas aeruginosa, a pathogen known for causing nosocomial infections. This metalloenzyme catalyzes the cis-trans isomerization of unsaturated fatty acids in order to rapidly modulate membrane fluidity in response to stresses that impede bacterial growth. As a consequence,...[more]