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[LSAMM] Synthèse des Assemblages Moléculaires Multifonctionnels

Responsable de l’équipe de recherche

Valérie HEITZ
Professeur à l'UdS

Année de création de l'équipe - 2010

Site de l’équipe de recherche

http://www.lsamm.fr/

Secrétariat et gestion assurés par

Geneviève STOLL
courriel : genstoll@unistra.fr
téléphone : 03 68 85 13 64

Personnels permanents

Personnels non permanents

Post-doctorante

  • SCHOEPFF Laetitia

Doctorants

  • JENNI Sébastien
  • DJEMILI Ryan

Thèmes de recherche

  • Molecular machines
  • Supramolecular coordination assemblies
  • Dynamic molecular cages
  • Bioactive Molecules for medical imagery and dynamic phototherapy
  • Photo- and electro- actives assemblies for the conversion of light energy to chemical energy

Descriptif de l'équipe de recherche

Our research group has a strong background in the synthesis of multi-component molecular and supramolecular systems. The choice of the components leads to electronic and photophysical properties for these architectures in order to make them suitable for:

  • Triggering a controlled motion of one of their components in order to create molecular machines;
  • Separating charges in long distances;
  • Applications in innovative medical therapies.

Our group is happy to welcome students interested in being involved in projects related to molecular and supramolecular synthesis using organic and organometallic chemistry.

Our group possesses all necessary equipment to perform organic chemistry, coordination chemistry and for the purification of the synthesized molecular systems.

Sélection de publications marquantes

F. Bolze, S. Jenni, A. Sour, V.Heitz
Molecular photosensitisers for two-photon photodynamic therapy
Chem. Commun.201753, 12857-12877 (Feature article)

L. Schoepff, L. Kocher, S. Durot, V. Heitz
Chemically-induced breathing of flexible porphyrinic covalent cages
J. Org. Chem., 201782, 5845–5851

J. Schmitt, V. Heitz, A. Sour, F. Bolze, P. Kessler, L. Flamigni, B. Ventura, C. Bonnet, E. Tóth
A theranostic agent combining a two-photonabsorbing photosensitizer for photodynamic therapy and a gadolinium(III) complex for MRI detection
Chem. Eur. J. 
201622, 2775-2786

L. Kocher, S. Durot, V. Heitz
Control of the cavity size of flexible covalent cages by silver coordination to the peripheral binding sites
Chem. Commun.
201551, 13181-13184

J. Schmitt, V. Heitz, S. Sour, F. Bolze, H. Ftouni, J.-F. Nicoud, L. Flamigni, B. Ventura
Diketopyrrolopyrrole-porphyrin conjugates with high two-photon absorption and singlet oxygen generation for two-photon photodynamic therapy
Angew. Chem. Int. Ed. 201554, 169-173

Galerie photos de l'équipe de recherche

Un petit aperçu de notre équipe de recherche