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[ECMC] Confinement Moléculaire et Catalyse

Head of the research group

Dominique ARMSPACH
Professeur à l'Université de Strasbourg

Year of creation of the group - 2017

Group's website

 http://armspach.com/

Location

Le Bel Institute, 6th floor North

Secretarial and accounting services provided by

Agnès REIFFSTECK
email : reiffste@unistra.fr
Phone : +33 (0)3 68 85 14 32

Permanent members

  • Dominique ARMSPACH
    Professeur à l'Université de Strasbourg
    email: d.armspach@unistra.fr
    Phone: +33 (0)3 68 85 16 21

  • Katrin PELZER
    Chargée de recherche CNRS
    email: kpelzer@unistra.fr
    Phone: +33 (0)3 68 85 13 19

  • Pierre BRAUNSTEIN
    Directeur de recherche émérite au CNRS Classe Exceptionnelle
    Professeur conventionné à l'Université de Strasbourg
    Membre de l'Académie des Sciences
    Ancien directeur du LCC (https://lcc.chimie.unistra.fr/)
    email :braunstein@unistra.fr
    Phone:+33 (0)3 68 85 13 08
  • Geordie CRESTE*
    Assistant Ingénieur au CNRS
    email : creste@unistra.fr
    Phone : +33 (0)3 68 85 11 33

 * travaille pour plusieurs équipes

Description of the research group

The "Confinement Moléculaire et Catalyse" (ECMC) group’s interests lie in the synthesis of confining molecules mainly in order to develop highly selective catalysts.  ECMC is a multidisciplinary group which focuses on topics as varied as organic synthesis, coordination chemistry, homogeneous catalysis, organocatalysis and supramolecular chemistry within the general context of green chemistry and sustainable development.  Undergraduate students (DUT and L3) as well as masters students (M1 and M2) interested in molecular synthesis are most welcome to apply for two - six month placements.


Research topics

  • Glycochemistry (modification of cyclodextrins)
  • Synthesis and coordination chemistry of confining ligands
  • Synthesis of luminescent metal complexes
  • Organometallic catalysis

              - Asymmetric hydrogenation and hydroformylation of olefins

              - Oligomerization and polymerization of olefins

              - C-C bond formation (Suzuki-Miyaura, Heck, ...)

              - Asymmetric gold catalysis

  • Supramolecular chemistry

              -  Supramolecular assemblies of cyclodextrins for therapeutic purposes

List of equipment and instruments

The ECMC group has four modern laboratories at its disposal. Each of them has three fume cupboards fully equipped for molecular synthesis (electricity, vacuum/argon line, compressed air, water).

It also has access to key equipment such as:

  • Gas chromatographs
  • Analytical HPLC chain (chiral columns, reverse and normal phases)
  • Glove boxes under argon atmosphere
  • High pressure autoclaves

Recent publications

G. Preda, S. Jung, G. Pescitelli, L. Cupellini, D. Armspach, D. Pasini 
Enabling stereochemical communication and stimuli-responsive chiroptical properties in biphenyl-capped cyclodextrins 
Chem. Eur. J. 2023, e202302376 (https://doi.org/10.1002/chem.202302376)

T. A. Phan, N. Armaroli, A. S. Moncada, E. Bandini, B. Delavaux-Nicot, J. F. Nierengarten, D. Armspach
Stable luminescent [Cu(NN)(PP)]+ complexes incorporating a β-cyclodextrin-based diphosphane Ligand with metal-confining properties
Angew. Chem. Int. Ed. 2023, 62, e202214638 (https://doi.org/10.1002/anie.202214638)

Z. Kaya, E. Bentouhami, K. Pelzer, D. Armspach
Cavity-shaped ligands for asymmetric metal catalysis
Coord. Chem. Rev. 2021, 445, 214066 (https://doi.org/10.1016/j.ccr.2021.214066)

Z. Kaya, L. Andna, D. Matt, E. Bentouhami, J.-P. Djukic, D. Armspach
A comparative study of confining ligands derived from methylated cyclodextrins in gold-catalyzed cycloisomerization of 1,6-enynes
Eur. J. Org. Chem. 2019, 4528–4537 (https://doi.org/10.1002/ejoc.201900631)

Z. Kaya, L. Andna, D. Matt, E. Bentouhami, J.-P. Djukic, D. Armspach
Benzimidazolium‐ and benzimidazolilydene‐capped cyclodextrins: new perspectives in anion encapsulation and gold‐catalyzed cycloisomerization of 1,6‐enynes
Chem. Eur. J. 2018, 17921-17926 (https://10.1002/chem.201804710)

D. Sechet, Z. Kaya, T. A. Phan, M. Jouffroy, E. Bentouhami, D. Armspach, D. Matt, L. Toupet
Aza-capped cyclodextrins for intra-cavity metal complexation
Chem. Commun. 2017, 11717-11720 (https://doi.org/10.1039/C7CC06434A)

M. Jouffroy, D. Armspach, D. Matt, K. Osakada, D. Takeuchi
Synthesis of optically active polystyrene catalyzed by monophosphine Pd complexes
Angew. Chem. Int. Ed. 2016, 55, 8367-8370 (https://doi.org/10.1002/anie.201603191)

M. Jouffroy, D. Armspach, D. Matt
Cyclodextrin and phosphorus(III): a versatile combination for coordination chemistry and catalysis
Dalton Trans. 2015, 44, 12942-12969 (https://doi.org/10.1039/C5DT00667H)

M. Jouffroy, R. Gramage-Doria, D. Armspach, D. Sémeril, W. Oberhauser, D. Matt, L. Toupet
Confining phosphanes derived from cyclodextrins for efficient regio- and enantioselective hydroformylation
Angew. Chem. Int. Ed. 2014, 53, 3937-3940 (https://doi.org/10.1002/anie.201311291)

 

Recent publications of PB are listed on the LCC website (https://lcc.chimie.unistra.fr/).