Vous êtes ici : Accueil   >   Actualités de l'institut   >   Publications récentes

Publications récentes

juil. 1 2021

Organic Letters [SOPhy]

Abstract : The significance of molecules containing difluoromethyl groups is driven by their potential applications in pharmaceutical and agrochemical science. Methods for the incorporation of lightly fluorinated groups such as CF2H have been less well developed. Here we report the use of difluorinated diazoacetone as a practical reagent for the direct synthesis of CF2H-substituted 2-amidofurans...[En savoir plus]

juin 29 2021

Coordination Chemistry Reviews [ECMC]

Abstract : Cavity-shaped ligands offer unique opportunities for influencing the first sphere of coordination of metals because of their capacity to act as containers for metal centers and/or preorganization platforms. These unique properties are of particular importance in asymmetric metal catalysis where spatial control around the coordinated substrate is of paramount importance for reaching...[En savoir plus]

juin 28 2021

Phys. Chem. Chem. Phys. [POMAM]

Abstract : A 16-line pattern has been theoretically predicted, but hitherto not reported, for the Electron Paramagnetic Resonance (EPR) spectrum of antiferromagnetically coupled CuII triangles experiencing isotropic exchange of isosceles magnetic symmetry. Now, the crystallization of such a triangular species and its X-ray structure determination in a polar space group, R3 (No. 146), has enabled...[En savoir plus]

mai 10 2021

J. Inorg. Biochem. [BCB]

Abstract: The measurement of labile CuII in biological samples is fundamental for understanding Cu metabolism and has been emerging as a promising diagnostic marker for Cu-related pathologies such as Wilson's and Alzheimer's diseases. The use of fluorescent chelators may be useful to circumvent separation steps employed by current methods. For this purpose, we recently designed a selective and...[En savoir plus]

avril 1 2021

J. Phys. Chem. Lett. [IFM]

Tweet : The IFM team proposes a novel mechanism of operation in a synthetic molecular muscle based on all-atom Molecular Dynamics and free energy calculations. Abstract : The design of molecular architectures exhibiting functional motions is a promising area for disruptive technological development. Toward this goal, rotaxanes and catenanes, which undergo relative motions of their subunits in...[En savoir plus]

mars 12 2021

J. Inorg. Biochem. [BCB / Biophysique des membranes et RMN]

Abstract : Depending on the coordination, copper ions can have a very high activity in catalyzing the production of reactive oxygen species. Thus interest arose in increasing the activity of antimicrobial peptides (AMPs) by equipping them with a Cu-binding unit. Several examples, native and engineered, have been investigated with the motif Xxx-Zzz-His, called Amino Terminal Cu(II)- and...[En savoir plus]

mars 12 2021

Coord. Chem. Rev. [BCB]

Abstract : Copper (Cu) is an essential micronutrient for most organisms and serves mainly as a redox-active catalytic centre in enzymes cycling between Cu+ and Cu2+. Membrane transporters and shuttles are involved to bring and insert Cu into these enzymes and to control tightly the copper metabolism, whose failure can lead to severe diseases. The main oxidation state intracellularly is Cu+,...[En savoir plus]

Précédente

1

2

3

4

5

6

7

8

9

10

Suivante