Abstract: A ß-cyclodextrin-based diphosphane with metal confining properties was efficiently synthesized thanks to an unprecedented Smiles-like rearrangement of 1-diphenylphosphino-2-phosphinobenzene in the presence of excess n-BuLi. The cis-chelating bidentate ligand is capable of forming very stable heteroleptic [Cu(NN)(PP)]+ complexes in which a metal-bound diimine ligand (bpy, phen or mmp)...[En savoir plus]
Regarding the POMAM’s article "A Magnetocaloric Glass from an Ionic-Liquid Gadolinium Complex" recently published in ChemPhysChem with a cover feature (https://doi.org/10.1002/cphc.202200356). The Institute of Chemistry is pleased to inform you that this work has also been selected to appear in the “Actualités de l’INC” of November 2022. Contact : Athanassios K. Boudalis, équipe Propriétés...[En savoir plus]
Comprehensive Organometallic Chemistry IV (Fourth Edition) N-Heterocyclic Carbene Complexes of Nickel Volume 8, 2022, Pages 427-574 - DOI: https://doi.org/10.1016/B978-0-12-820206-7.00118-9 Ligielli Irene, Danopoulos Andreas A., Braunstein Pierre and Simler Thomas Abstract: The impact of N-heterocyclic carbene (NHC) ligands across the Periodic Table in the last twenty years can be compared...[En savoir plus]
Comprehensive Organometallic Chemistry IV (Fourth Edition) N-Heterocyclic Carbene Complexes of Cobalt Volume 7, 2022, Pages 632-758- DOI: https://doi.org/10.1016/B978-0-12-820206-7.00109-8 Simler Thomas, Danopoulos Andreas A. and Braunstein Pierre Abstract: N-heterocyclic carbenes (NHCs) have become ubiquitous ligands across the Periodic Table and enjoy a growing impact on various aspects...[En savoir plus]
Abstract: The two-faced reactivity of N-allenamides allows regio-and stereo-controlled functionalization on the a-, b- and γ-positions of the nitrogen atom. The contingency to obtain either proximal or distal adducts, makes those substrates essential for the construction of complex heterocyclic scaffolds. This review covers recent advances made in the development of new methods involving...[En savoir plus]
Abstract: The progressive, neurodegenerative Alzheimer’s disease (AD) is the most widespread dementia. Due to the ageing of the population and the current lack of molecules able to prevent or stop the disease, AD will be even more impactful for society in the future. AD is a multifactorial disease, and, among other factors, metal ions have been regarded as potential therapeutic targets. This is...[En savoir plus]
Abstract: Copper (Cu) in its ionic forms is an essential element for mammals and its homeostasis is tightly controlled. Accordingly, Cu-dyshomeostasis can be lethal as is the case in the well-established genetic Wilson's and Menkes diseases. In Alzheimer's disease (AD), Cu-accumulation occurs in amyloid plaques, where it is bound to the amyloid-beta peptide (Aβ). In vitro, Cu–Aβ is competent to...[En savoir plus]