- Présentation
- Équipes de Recherche
- Biogéochimie moléculaire
- [BCB] Biométaux et Chimie Biologique
- [CLIC] Coordination, Ligands, Interactions et Catalyse
- [CBMB] Chimie et Biochimie de Molécules Bioactives
- [LCQS] Chimie Quantique de Strasbourg
- [LECPCS] Electrochimie et Chimie Physique du Corps Solide
- [COSyS] Catalyse Organométallique, Synthèse organique et Santé
- [SOPhy] Synthèse Organique & Phytochimie
- [LSAMM] Synthèse des Assemblages Moléculaires Multifonctionnels
- [LCSOM] Chimie et Systémique Organo-Métalliques
- [CBAT] Chimie Biologique et Applications Thérapeutiques
- [ECMC] Confinement Moléculaire et Catalyse
- [POMAM] Propriétés Optiques et Magnétiques des Architectures Moléculaires
- Biophysique des membranes et RMN
- [IFM] Laboratoire d’Ingénierie des Fonctions Moléculaires
- [SRCO] Synthèse, Réactivité et Catalyse Organométalliques
- [OMECA] Objets, MEtaux et CAtalyse
- [SOCAT] Synthèse Organométallique et CATalyse
- Services scientifiques
- Actualités de l'institut
- Agenda - Conférences
- Annuaires CNRS et Université
Abstract: The discovery of a stable organic radical formed under mild, clean,...
Abstract: In this review, the difference between π-mers (pimers) and π-dimers...
Publications récentes
Journal of the American Chemical Society [LSAMM / POMAM / LECPCS]
Abstract: The discovery of a stable organic radical formed under mild, clean, and efficient light-mediated conditions is reported. The structure of the stable acridinium-based radical photoproduct was unambiguously established by single-crystal X-ray diffraction, mass spectrometry, and in solution by EPR, UV/vis, and NMR spectroscopies. The photochemical mechanism of its formation has been...[En savoir plus]
Chemistry – A European Journal [LSAMM / CLIC]
Abstract: In this review, the difference between π-mers (pimers) and π-dimers (pi-dimers) will be discussed. Often interchanged or confused in the literature, these two radical interactions lead to different or even opposite physico-chemical behaviors. This review aims at clarifying the terms π-mers and π-dimers and at describing their main physico-chemical properties to address their...[En savoir plus]
Inorganic Chemistry [BCB/POMAM]
Abstract: Imaging extracellular Cu2+ in vivo is of paramount interest due to its biological importance in both physiological and pathological states. Magnetic resonance imaging (MRI) is a powerful technique to do so. However, the development of efficient MRI contrast agents selective for Cu2+, particularly versus the more abundant Zn2+ ions, is highly challenging. We present here an innovative...[En savoir plus]
ChemBioChem [CBAT/Biogéochimie moléculaire]
Abstract: The lipid cis-trans isomerase (Cti) is a periplasmic heme-c enzyme found in several bacteria including Pseudomonas aeruginosa, a pathogen known for causing nosocomial infections. This metalloenzyme catalyzes the cis-trans isomerization of unsaturated fatty acids in order to rapidly modulate membrane fluidity in response to stresses that impede bacterial growth. As a consequence,...[En savoir plus]
Chem. Eur. J. [POMAM / CLIC]
Abstract: The use of VIV and CuII spins to design weakly coupled and dissymmetric spin systems has been examined. Such systems were synthesized using porphyrin-based complexes, with external coordination sites allowing for the formation of dimers via a PdII linker ion. Continuous-wave (CW) Electron Paramagnetic Resonance (EPR) spectroscopy allowed the unequivocal magnetic characterization of the...[En savoir plus]
ACS Infectious Diseases [CBAT]
Abstract: Antimicrobial resistance (AMR) poses a serious threat to global health. The rapid emergence of resistance contrasts with the slow pace of antimicrobial development, emphasizing the urgent need for innovative drug discovery approaches. This study addresses a critical bottleneck in early drug development by introducing integral solvent-induced protein precipitation (iSPP) to rapidly...[En savoir plus]
Org. Chem. Front. [SOPhy]
Abstract: A totally controlled regiodivergent azidation of activated N-allenamides is presented. Using TMSN3/TBAF, β-azidation of N-allenamides occurs exclusively, yielding vinyl azides. Conversely, employing a TFA/TMSN3 mixture results solely in the formation of γ-azides. A subsequent formal Winstein rearrangement of the latter with DBU produces α-amido vinyl azides. Additionally,...[En savoir plus]