Dalton Transactions [CLIC / POMAM / LECPCS]

Absract:

Iron-copper complexes have been extensively studied in the search for efficient cytochrome c oxidase models. Whereas most dinuclear materials usually focus on fine-tuning the coordination of heme-Fe, this work shows that the coordination of copper in cytochrome c oxidase models should be carefully taken into consideration. A β-cyclodextrin dimer was built around a bipyridine linker and combined with Fe-tetraphenylsulfonatoporphyrinate (FeTPPS) to generate a self-assembled hydrosoluble cytochrome c oxidase model. Cyclic voltammetry and rotating ring disk electrode experiments showed that this model with a tetrahedral coordination of copper(I) is efficient for the reduction of molecular oxygen with an average of 3.6 electrons indicating a preference and efficiency for the four-electron reduction to water.

Reference:

Insight into copper coordination in O₂ reduction by water-soluble cytochrome c oxidase models

Mathilde BERTHE, Corinne BOUDON, Nolwenn LE BRETON, Hiroaki KITAGISHI, Koji OOHORA, Takashi HAYASHI, Jennifer A. WYTKO,  and Jean WEISS

Dalton Trans., first published on 16 January 2025, Advance Article – DOI: https://doi.org/10.1039/D4DT03188A

 

Contacts:

Jennifer A. WYTKO & Jean WEISS (équipe Coordination, Ligands, Interactions et Catalyse, CLIC), Institut de Chimie de Strasbourg, UMR 7177.