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[ECMC] Confinement Moléculaire et Catalyse

Head of the research group

Dominique ARMSPACH
Professeur à l'Université de Strasbourg

Year of creation of the group - 2017

Group's website

 http://armspach.com/

Secretarial and accounting services provided by

Elisabeth VACCARO
email : vaccaro@unistra.fr
Phone : +33 (0)3 68 85 16 84

Permanent members

Non-permanent members

PhD students

  • Tuan-Anh PHAN
  • Zeyneb KAYA

Description of the research group

The "Confinement Moléculaire et Catalyse" (ECMC) group’s interests lie in the synthesis of confining molecules mainly in order to develop highly selective catalysts.  ECMC is a multidisciplinary group which focuses on topics as varied as organic synthesis, coordination chemistry, homogeneous catalysis, organocatalysis and supramolecular chemistry within the general context of green chemistry and sustainable development.  Undergraduate students (DUT and L3) as well as masters students (M1 and M2) interested in molecular synthesis are most welcome to apply for two - six month placements.


Research topics

  • Glycochemistry (modification of cyclodextrins)
  • Synthesis and coordination chemistry of confining ligands
  • Synthesis of luminescent metal complexes
  • Organometallic catalysis

              - Asymmetric hydrogenation and hydroformylation of olefins

              - Oligomerization and polymerization of olefins

              - C-C bond formation (Suzuki-Miyaura, Heck, ...)

              - Asymmetric gold catalysis

              - Synthesis of rotaxanes by the active metal template strategy

  • Organocatalysis

              - Asymmetric epoxidation

              - Asymmetric phase transfer catalysis

              - Asymmetric aldolization reactions

  • Homogeneous or biphasic catalysis in unusual media

List of equipment and instruments

The ECMC group has four modern laboratories at its disposal. Each of them has three fume cupboards fully equipped for molecular synthesis (electricity, vacuum/argon line, compressed air, water).

It also has access to key equipment such as:

  • Gas chromatographs
  • Analytical HPLC chain (chiral columns, reverse and normal phases)
  • Glove boxes under argon atmosphere
  • High pressure autoclaves

Recent publications

M. Jouffroy, D. Armspach, D. Matt, K. Osakada, D. Takeuchi
Synthesis of optically active polystyrene catalyzed by monophosphine Pd complexes
Angew. Chem. Int. Ed. 2016, 55, 8367-8370

M. Jouffroy, D. Armspach, D. Matt
Cyclodextrin and phosphorus(III): a versatile combination for coordination chemistry and catalysis
Dalton Trans. 2015, 44, 12942-12969

M. Jouffroy, R. Gramage-Doria, D. Armspach, D. Sémeril, W. Oberhauser, D. Matt, L. Toupet
Confining phosphanes derived from cyclodextrins for efficient regio- and enantioselective hydroformylation
Angew. Chem. Int. Ed.
2014, 53, 3937-3940

M. Jouffroy, D. Armspach, A. Louati, D. Matt, L. Toupet
Capping methodology in cyclodextrin chemistry: Use of a symmetrical diketone reagent for regiospecific installation of unsymmetrical imine-enamine and imidazole caps
Chem. Eur. J. 2014, 20, 2565-2573

R. Gramage-Doria, D. Armspach, D. Matt
Metallated cavitands (calixarenes, resorcinarenes, cyclodextrins) with internal coordination sites
Coord. Chem. Rev. 2013, 257, 776-816

R. Gramage-Doria, D. Armspach, D. Matt, L. Toupet
TRANSDIP: a trans-chelating ligand tailor-made for probing unusual Pd0 and PdII intermediates
Chem. Eur. J. 2012, 18, 10813-10816

M. Jouffroy, R. Gramage-Doria, D. Armspach, D. Matt, L. Toupet
Regioselective opening of proximally sulfato-capped cyclodextrins
Chem. Commun. 2012, 48, 6028-6030

R. Gramage-Doria, D. Armspach, D. Matt, L. Toupet
A cavity-shaped diphosphane displaying “oschelating” behavior
Angew. Chem. Int. Ed. 2011, 50, 1554-1559

Recent publications of PB and MW are listed on the LCC website (http://institut-chimie.unistra.fr/equipes-de-recherche/lcc-chimie-de-coordination/).