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Conférence Dr Frank BIEDERMANN (ED222)

Le 4 mai 2018
À 10h30
Salle verte

Dans le cadre des conférences de l’Ecole Doctorale Sciences Chimiques (ED 222), nous avons le plaisir d’accueillir le vendredi 4 mai à 10h30, Salle verte

Dr Frank BIEDERMANN

 

"Supramolecular Chemosensing Ensembles: More Information through Communication"

(Institute of Nanotechnology, Karlsruhe Institute of Technology)


ABSTRACT

Supramolecular Chemosensing Ensembles: More Information through Communication

In this talk, we present new supramolecular chemosensing ensembles that can be utilized for the detection of spectroscopically silent analytes in aqueous media. This enabled the development of versatile reactive-probe assays, indicator-displacement assays and associative-binding assays.1, 2
Starting from fundamental considerations and practical requirements, we show the development of chemosensors that can be used for the detection of drugs in blood serum and the label-free monitoring of biochemical/biophysical processes in real-time.3, 4

  1. Sinn S, Biedermann F. Chemical Sensors Based on Cucurbit[n]uril Macrocycles. Isr. J. Chem. 2018, in press & patend pending.

  2. Sinn S, Biedermann F, De Cola L. Platinum Complex Assemblies as Luminescent Probes and Tags for Drugs and Toxins in Water. Chem. Eur. J. 2017, 23, 1965.

  3. Lazar AI, Biedermann F, Mustafina KR, Assaf KI, Hennig A, Nau WM. Nanomolar Binding of Steroids to Cucurbit[n]urils: Selectivity and Applications. J. Am. Chem. Soc. 2016, 138, 13022.

  4. Biedermann F, Nau WM. Noncovalent Chirality Sensing Ensembles for the Detection and Reaction Monitoring of Amino Acids, Peptides, Proteins, and Aromatic Drugs. Angew. Chem. Int. Ed. 2014, 53, 5694 & patented.