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Publications récentes

janv. 12 2018


New paradigm for potency :  The crystal structures of E.coli IspH in complex with (E)-4-mercapto-3-methylbut-2-en-1-yl diphosphate enable us to design IspH ligands with improved binding capacities.  A novel binding feature gave rise to compounds that present a new paradigm for the development of more potent IspH inhibitors.     Réference: Franck Borel, Elodie Barbier, Sergiy Krasutsky,...[En savoir plus]

déc. 13 2017


graphical abstract

Référence: F. Bolze, S. Jenni, A. Sour and V. Heitz Molecular photosensitisers for two-photon photodynamic therapy Chem. Commun., 2017, 53, 12857 (DOI: 10.1039/c7cc06133a)   Contact chercheur: Valérie Heitz, Institut de Chimie de Strasbourg Courriel: v.heitz@unistra.fr[En savoir plus]

déc. 11 2017

Coordination Chemistry Reviews


Référence: Chantal Daniel and Christophe Gourlaouen Chemical bonding alteration upon electronic excitation in transition metal complexes Coordination Chemistry Reviews, 2017, 344, 131-149 (https://doi.org/10.1016/j.ccr.2016.10.010)   Contact chercheur:Chantal Daniel, Institut de Chimie de StrasbourgCourriel: c.daniel@unistra.fr[En savoir plus]

nov. 17 2017



Référence: Alice Santoro, Nina Ewa Wezynfeld, Milan Vašak, Wojciech Bal and Peter Faller Cysteine and glutathione trigger the Cu–Zn swap between Cu(II)-amyloid-β4-16 peptide and Zn7-metallothionein-3 Chem. Commun., 2017,53, 11634-11637 (http://dx.doi.org/10.1039/C7CC06802F)   Contact chercheur: Peter Faller, Institut de Chimie de Strasbourg Courriel: pfaller@unistra.fr   [En savoir plus]

nov. 17 2017

ACS Omega

Structural characterization of the amyloid precursor protein transmembrane domain and its gamma-cleavage site Anna Itkin,  Evgeniy S. Salnikov, Christopher Aisenbrey, Jesus Raya, Elise Glattard, Vincent Raussens, Jean-Marie Ruysschaert, Burkhard Bechinger ACS Omega, 2017, 2 (10), pp 6525–6534 (team Membrane biophysics and NMR):   Alzheimer’s disease is the most common form of dementia that...[En savoir plus]

oct. 3 2017

Dalton Transactions


Can you melt a magnet? Researchers from the Institut de Chimie, have reported magnetic liquids that are neither solutions nor suspensions, but low-melting magnetic salts. This work was featured by the science blog "The Surg" with the title "Can you melt a magnet?" (https://thesurg.com/can-you-melt-magnet/) and hopefully will provide ideas for the deployment of magnetic materials in the liquid...[En savoir plus]

août 23 2017

Chemistry : A European Journal

Copper-induced alkyne-azide cycloaddition (CuAAC), popularly known as the click-reaction, is one of the most widely used synthetic methods in the design of supramolecular scaffoldings. Whether its catalytic or stoichiometric version is concerned, the involvement of two metals in the cycloaddition has been debated in the literature in the case of copper and other metals such as zinc. Research...[En savoir plus]