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Actualités de l'institut

mars 6 2020

"Ma thèse en 180 secondes" édition Alsace

Finale régionale "Ma thèse en 180 secondes" De jeunes chercheuses et chercheurs vont relever le défi de vous présenter leur projet de recherche de manière claire et accessible, en 3 minutes et avec l'appui d'une seule diapositive, à l’occasion de l’édition alsacienne du concours « Ma thèse en 180 secondes ».   Cette finale régionale MT180 aura lieu jeudi 19 mars à 18h30, à l’amphithéâtre...[En savoir plus]

mars 4 2020

Actualités de l’INC [POMAM]

Regarding the POMAM’s group article “Polyanisotropic magnetoelectric coupling in an electrically controlled molecular spin qubit” recently published and chosen for the front cover of JACS Volume 141, Issue 50 (December 18, 2019).   The Institute of Chemistry of Strasbourg (UMR7177), is proud to inform you that this article has also been selected to appear in the “Actualités de l’INC” of March...[En savoir plus]

mars 3 2020

Angew. Chem. Int. Ed. [BCB]

Abstract: Copper-complexes are of medicinal and biological interest, including as anticancer drugs designed to cleave intracellular biomolecules via O2 activation. To exhibit such activity, the copper complex must be redox-active and resistant to dissociation. Metallothioneins (MTs) and glutathione (GSH) are abundant in the cytosol and nucleus. Because they also are thiol-rich reducing molecules...[En savoir plus]

janv. 21 2020

Chemistry Eur. J. [CBAT/RMN]

Abstract: IspH/LytB, an oxygen‐sensitive [4Fe‐4S] enzyme, catalyzes the last step of the methylerythritol phosphate (MEP) pathway, a target for the development of new antimicrobial agents. This metalloenzyme converts (E)‐4‐hydroxy‐3‐methylbut‐2‐en‐1‐yl diphosphate (HMBPP) into the two isoprenoid precursors: isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Here, the synthesis...[En savoir plus]

janv. 13 2020

J. Mat. Chem. C [LECPCS]

Abstract: A series of three new polyoxometalate/spiromolecule compounds – including the (TBA)3[AlMo6-SN] (SN = spironaphthoxazine) and (TBA)3[AlMo6-SP] (SP = spiropyran) Anderson-type polyoxometalates (POMs) and the unprecedented (TBA)5[P2W15V3-SP] Dawson-type species – has been synthesized and characterized using a full panel of techniques. These hybrids have been thoroughly investigated by...[En savoir plus]

déc. 19 2019

Chemistry Eur. J. [BCB /POMAM]

Abstract: Mounting evidence supports the role of amyloidogenesis, oxidative stress, and metal dyshomeostasis in the development of neurodegenerative disorders. Parkinson's Disease is characterized by α-Synuclein (αSyn) accumulation and aggregation in brain regions, also promoted by Cu2+. αSyn is modified by reactive carbonyl species, including acrolein (ACR). Notwithstanding these findings, the...[En savoir plus]

déc. 19 2019

Organic Geochemistry [Biogéochimie moléculaire]

Abstract: The widely distributed aromatic di- and triterpenoids from higher plants occurring in sediments are formed by diagenetic microbial processes affecting their precursor plant lipids. These compounds and their stable isotopic composition (δ13C and δ2H) have the potential to be used for palaeoenvironmental and palaeoclimatic studies. In the present study, the isotopic composition of di-...[En savoir plus]